8C41

High resolution structure of the Streptococcus pneumoniae topoisomerase IV-DNA complex with the novel fluoroquinolone Delafloxacin

8C41 の概要

• エントリーDOI: 10.2210/pdb8c41/pdb
• 分子名称: Fused ParE30ParC55 CLEAVAGE COMPLEX of the TOPOISOMERASE IV, DNA (5'-D(*CP*AP*TP*GP*AP*AP*T)-3'), DNA (5'-D(P*AP*GP*TP*CP*AP*TP*TP*CP*AP*TP*G)-3'), ... (10 entities in total)
• 機能のキーワード: protein-dna cleavage complex, topoisomerase iia, delafloxacin, topoisomerase iv-dna-antibiotic complex, isomerase
• 由来する生物種: Streptococcus pneumoniae; 詳細
• タンパク質・核酸の鎖数: 6
• 化学式量合計: 180816.89

構造登録者

Najmudin, S.,Pan, X.S.,Wang, B.,Chayen, N.E.,Fisher, L.M.,Sanderson, M.R. (登録日: 2022-12-30, 公開日: 2024-01-10, 最終更新日: 2024-01-24)

• 主引用文献: Najmudin, S.,Pan, X.S.,Wang, B.,Chayen, N.E.,Fisher, L.M.,Sanderson, M.R.; The nature of the molecular interactions at high resolution of the Streptococcus pneumoniae topoisomerase IV-DNA complex with the novel fluoroquinolone Delafloxacin.; To Be Published,

実験手法

X-RAY DIFFRACTION (2.393 Å)