8C37

An intermediate light exposed 2.15 Angstrom crystal structure of H132A variant of cobalamin binding domain belonging to a light-dependent transcription regulator TtCarH obtained under anaerobic conditions

Summary for 8C37

Entry DOI	10.2210/pdb8c37/pdb
Descriptor	Probable transcriptional regulator, COBALAMIN (3 entities in total)
Functional Keywords	carh, cobalamin, light-activated, transcription regulator, anaerobic, transcription
Biological source	Thermus thermophilus
Total number of polymer chains	4
Total formula weight	98092.34
Authors	Poddar, H.,Leys, D. (deposition date: 2022-12-23, release date: 2023-08-16, Last modification date: 2023-08-30)
Primary citation	Poddar, H.,Rios-Santacruz, R.,Heyes, D.J.,Shanmugam, M.,Brookfield, A.,Johannissen, L.O.,Levy, C.W.,Jeffreys, L.N.,Zhang, S.,Sakuma, M.,Colletier, J.P.,Hay, S.,Schiro, G.,Weik, M.,Scrutton, N.S.,Leys, D. Redox driven B 12 -ligand switch drives CarH photoresponse. Nat Commun, 14:5082-5082, 2023 Cited by PubMed: 37604813 DOI: 10.1038/s41467-023-40817-6 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (2.15 Å)

Structure validation