8C1R
Resting state homomeric GluA2 F231A mutant AMPA receptor in complex with TARP gamma-2
Summary for 8C1R
Entry DOI | 10.2210/pdb8c1r/pdb |
EMDB information | 16381 |
Descriptor | Glutamate receptor 2, Voltage-dependent calcium channel gamma-2 subunit, {[7-morpholin-4-yl-2,3-dioxo-6-(trifluoromethyl)-3,4-dihydroquinoxalin-1(2H)-yl]methyl}phosphonic acid, ... (7 entities in total) |
Functional Keywords | ampar, ion channels, neurotransmission, membrane protein |
Biological source | Rattus norvegicus (Norway rat) More |
Total number of polymer chains | 8 |
Total formula weight | 551412.31 |
Authors | Zhang, D.,Ivica, J.,Krieger, J.M.,Ho, H.,Yamashita, K.,Cais, O.,Greger, I. (deposition date: 2022-12-21, release date: 2023-08-30, Last modification date: 2024-10-09) |
Primary citation | Zhang, D.,Ivica, J.,Krieger, J.M.,Ho, H.,Yamashita, K.,Stockwell, I.,Baradaran, R.,Cais, O.,Greger, I.H. Structural mobility tunes signalling of the GluA1 AMPA glutamate receptor. Nature, 621:877-882, 2023 Cited by PubMed: 37704721DOI: 10.1038/s41586-023-06528-0 PDB entries with the same primary citation |
Experimental method | ELECTRON MICROSCOPY (3.2 Å) |
Structure validation
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