8BZS

The crystal structure of glycogen phosphorylase in complex with baicalein

8BZS の概要

• エントリーDOI: 10.2210/pdb8bzs/pdb
• 分子名称: Glycogen phosphorylase, muscle form, PYRIDOXAL-5'-PHOSPHATE, 5,6,7-trihydroxy-2-phenyl-4H-chromen-4-one, ... (4 entities in total)
• 機能のキーワード: transferase
• 由来する生物種: Oryctolagus cuniculus (rabbit)
• タンパク質・核酸の鎖数: 1
• 化学式量合計: 97939.78

構造登録者

Koulas, S.M.,Mathomes, R.,Hayes, J.M.,Leonidas, D.D. (登録日: 2022-12-15, 公開日: 2023-09-13)

• 主引用文献: Mathomes, R.T.,Koulas, S.M.,Tsialtas, I.,Stravodimos, G.,Welsby, P.J.,Psarra, A.G.,Stasik, I.,Leonidas, D.D.,Hayes, J.M.; Multidisciplinary docking, kinetics and X-ray crystallography studies of baicalein acting as a glycogen phosphorylase inhibitor and determination of its' potential against glioblastoma in cellular models.; Chem.Biol.Interact., 382:110568-110568, 2023; PubMed: 37277066; DOI: 10.1016/j.cbi.2023.110568

実験手法

X-RAY DIFFRACTION (2.25 Å)