8BZ3

Structure od the carbohydrate reconition domain of Gal3 in comples with SAF-2-010

Summary for 8BZ3

Entry DOI	10.2210/pdb8bz3/pdb
Descriptor	Galectin-3, [(2~{S},3~{R},4~{S},5~{S},6~{R})-2-[(2~{R},3~{S},4~{R},5~{R},6~{S})-5-acetamido-2-(hydroxymethyl)-6-(4-nitrophenoxy)-4-oxidanyl-oxan-3-yl]oxy-6-(hydroxymethyl)-3,5-bis(oxidanyl)oxan-4-yl] hydrogen sulfate (3 entities in total)
Functional Keywords	gal3c, saf-2-010, sugar binding protein
Biological source	Homo sapiens (human)
Total number of polymer chains	1
Total formula weight	16933.30
Authors	Medrano, F.J.,Romero, A. (deposition date: 2022-12-14, release date: 2023-03-01, Last modification date: 2023-03-08)
Primary citation	Abdullayev, S.,Kadav, P.,Bandyopadhyay, P.,Medrano, F.J.,Rabinovich, G.A.,Dam, T.K.,Romero, A.,Roy, R. Selectively Modified Lactose and N -Acetyllactosamine Analogs at Three Key Positions to Afford Effective Galectin-3 Ligands. Int J Mol Sci, 24:-, 2023 Cited by PubMed: 36835132 DOI: 10.3390/ijms24043718 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (1.31 Å)

Structure validation