8BWD

Crystal structure of human Twisted gastrulation protein homolog 1 (TWSG1), crystal form 1

Summary for 8BWD

Entry DOI	10.2210/pdb8bwd/pdb
Descriptor	Twisted gastrulation protein homolog 1, SULFATE ION (3 entities in total)
Functional Keywords	twisted gastrulation protein homolog 1 (twsg1), transforming growth factor beta (tgf-beta) signalling pathway, extracellular protein, disulfide rich domains., signaling protein
Biological source	Homo sapiens (human)
Total number of polymer chains	2
Total formula weight	47235.58
Authors	Malinauskas, T.,Rudolf, A.F.,Moore, G.,Eggington, H.,Belnoue-Davis, H.,El Omari, K.,Woolley, R.E.,Griffiths, S.C.,Duman, R.,Wagner, A.,Leedham, S.J.,Baldock, C.,Ashe, H.,Siebold, C. (deposition date: 2022-12-06, release date: 2024-06-19)
Primary citation	Malinauskas, T.,Moore, G.,Rudolf, A.F.,Eggington, H.,Belnoue-Davis, H.L.,El Omari, K.,Griffiths, S.C.,Woolley, R.E.,Duman, R.,Wagner, A.,Leedham, S.J.,Baldock, C.,Ashe, H.L.,Siebold, C. Molecular mechanism of BMP signal control by Twisted gastrulation. Nat Commun, 15:4976-4976, 2024 Cited by PubMed: 38862520 DOI: 10.1038/s41467-024-49065-8 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (2.63 Å)

Structure validation