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8BSS

Solution Structure of thanatin-like derivative 5 in complex with E. coli LptA mutant Q62L

Summary for 8BSS
Entry DOI10.2210/pdb8bss/pdb
Related7QS6 7ZAX 7ZED
NMR InformationBMRB: 34773
DescriptorLipopolysaccharide export system protein LptA, Thanatin-like derivative (2 entities in total)
Functional Keywordsantibiotic
Biological sourceEscherichia coli K-12
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Total number of polymer chains2
Total formula weight16440.59
Authors
Oi, K.K.,Jurt, S.,Moehle, K.,Zerbe, O. (deposition date: 2022-11-26, release date: 2023-06-07, Last modification date: 2023-11-15)
Primary citationSchuster, M.,Brabet, E.,Oi, K.K.,Desjonqueres, N.,Moehle, K.,Le Poupon, K.,Hell, S.,Gable, S.,Rithie, V.,Dillinger, S.,Zbinden, P.,Luther, A.,Li, C.,Stiegeler, S.,D'Arco, C.,Locher, H.,Remus, T.,DiMaio, S.,Motta, P.,Wach, A.,Jung, F.,Upert, G.,Obrecht, D.,Benghezal, M.,Zerbe, O.
Peptidomimetic antibiotics disrupt the lipopolysaccharide transport bridge of drug-resistant Enterobacteriaceae.
Sci Adv, 9:eadg3683-eadg3683, 2023
Cited by
PubMed: 37224246
DOI: 10.1126/sciadv.adg3683
PDB entries with the same primary citation
Experimental method
SOLUTION NMR
Structure validation

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