8BSQ
Notum Inhibitor ARUK3006561
Summary for 8BSQ
Entry DOI | 10.2210/pdb8bsq/pdb |
Descriptor | Palmitoleoyl-protein carboxylesterase NOTUM, SULFATE ION, 2-acetamido-2-deoxy-beta-D-glucopyranose, ... (6 entities in total) |
Functional Keywords | inhibitor notum, hydrolase |
Biological source | Homo sapiens (human) |
Total number of polymer chains | 1 |
Total formula weight | 44662.09 |
Authors | Zhao, Y.,Jones, E.Y.,Fish, P. (deposition date: 2022-11-26, release date: 2022-12-14, Last modification date: 2023-06-28) |
Primary citation | Atkinson, B.N.,Willis, N.J.,Zhao, Y.,Patel, C.,Frew, S.,Costelloe, K.,Magno, L.,Svensson, F.,Jones, E.Y.,Fish, P.V. Designed switch from covalent to non-covalent inhibitors of carboxylesterase Notum activity. Eur.J.Med.Chem., 251:115132-115132, 2023 Cited by PubMed: 36934521DOI: 10.1016/j.ejmech.2023.115132 PDB entries with the same primary citation |
Experimental method |
Structure validation
Download full validation report![Download](/newweb/media/icons/dl.png)
![Download](/newweb/media/icons/dl.png)