8BSQ
Notum Inhibitor ARUK3006561
Entity
Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
1 | A | Palmitoleoyl-protein carboxylesterase NOTUM | polymer | 383 | 43567.1 | 1 | UniProt (Q6P988) Pfam (PF03283) In PDB | Homo sapiens (human) | hNOTUM |
2 | A | SULFATE ION | non-polymer | 96.1 | 5 | Chemie (SO4) | |||
3 | A | 2-acetamido-2-deoxy-beta-D-glucopyranose | non-polymer | 221.2 | 1 | Chemie (NAG) | |||
4 | A | DIMETHYL SULFOXIDE | non-polymer | 78.1 | 1 | Chemie (DMS) | |||
5 | A | ethyl 4-oxidanylidene-4-[4-(trifluoromethyl)-2,3-dihydroindol-1-yl]butanoate | non-polymer | 315.3 | 1 | Chemie (RDO) | |||
6 | water | water | 18.0 | 108 | Chemie (HOH) |
Sequence modifications
A: 81 - 451 (UniProt: Q6P988)
PDB | External Database | Details |
---|---|---|
Glu 78 | - | cloning artifact |
Thr 79 | - | cloning artifact |
Gly 80 | - | cloning artifact |
Ser 330 | Cys 330 | engineered mutation |
Gly 452 | - | expression tag |
Thr 453 | - | expression tag |
Lys 454 | - | expression tag |
His 455 | - | expression tag |
His 456 | - | expression tag |
His 457 | - | expression tag |
His 458 | - | expression tag |
His 459 | - | expression tag |
His 460 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
Polymers | Number of chains | 1 |
Total formula weight | 43567.1 | |
Non-Polymers* | Number of molecules | 8 |
Total formula weight | 1094.9 | |
All* | Total formula weight | 44662.1 |