8BRN

Crystal structure of red kidney bean purple acid phosphatase in complex with an alpha-aminonaphthylmethylphosphonic acid inhibitor

8BRN の概要

• エントリーDOI: 10.2210/pdb8brn/pdb
• 分子名称: Fe(3+)-Zn(2+) purple acid phosphatase, alpha-L-fucopyranose-(1-3)-2-acetamido-2-deoxy-beta-D-glucopyranose, ZINC ION, ... (23 entities in total)
• 機能のキーワード: metallohydrolase, phosphatase, metal binding protein
• 由来する生物種: Phaseolus vulgaris
• タンパク質・核酸の鎖数: 4
• 化学式量合計: 226076.82

構造登録者

Feder, D.,Hussein, W.M.,Guddat, L.W.,Schenk, G. (登録日: 2022-11-23, 公開日: 2023-08-02)

• 主引用文献: Feder, D.,Mohd-Pahmi, S.H.,Adibi, H.,Guddat, L.W.,Schenk, G.,McGeary, R.P.,Hussein, W.M.; Optimization of an alpha-aminonaphthylmethylphosphonic acid inhibitor of purple acid phosphatase using rational structure-based design approaches.; Eur.J.Med.Chem., 254:115383-115383, 2023; PubMed: 37087894; DOI: 10.1016/j.ejmech.2023.115383

実験手法

X-RAY DIFFRACTION (2 Å)