8BOW

X-ray structure of human glutamate carboxypeptidase II (GCPII) in complex with an inhibitor 617

Summary for 8BOW

• Entry DOI: 10.2210/pdb8bow/pdb
• Descriptor: Glutamate carboxypeptidase 2, (2~{S})-2-[[(2~{S})-6-[[(2~{S})-3-naphthalen-2-yl-2-[[4-[[2-[(11~{Z})-4,7,10-tris(2-hydroxy-2-oxoethyl)-1,4,7,10-tetrazacyclododec-11-en-1-yl]ethanoylamino]methyl]cyclohexyl]carbonylamino]propanoyl]amino]-1-oxidanyl-1-oxidanylidene-hexan-2-yl]carbamoylamino]pentanedioic acid, beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, ... (11 entities in total)
• Functional Keywords: glutamate carboxypeptidase ii (gcpii); naaladase; prostate-specific membrane antigen; inhibitor, hydrolase
• Biological source: Homo sapiens (human)
• Total number of polymer chains: 1
• Total formula weight: 84544.63

Authors

Motlova, L.,Barinka, C.,Benesova, M. (deposition date: 2022-11-15, release date: 2023-11-29, Last modification date: 2024-10-16)

• Primary citation: Motlova, L.,Barinka, C.,Benesova, M.; X-ray structure of human glutamate carboxypeptidase II (GCPII) in complex with an inhibitor 617; To Be Published,

Experimental method

X-RAY DIFFRACTION (1.58 Å)