8BO8

X-ray structure of human glutamate carboxypeptidase II (GCPII) in complex with an inhibitor P17

Summary for 8BO8

• Entry DOI: 10.2210/pdb8bo8/pdb
• Descriptor: Glutamate carboxypeptidase 2, SODIUM ION, (2~{S})-2-[[(2~{S})-1-oxidanyl-1-oxidanylidene-6-[[(~{E},2~{S})-5-phenyl-2-[[4-[[2-[4,7,10-tris(2-hydroxy-2-oxoethyl)-1,4,7,10-tetrazacyclododec-1-yl]ethanoylamino]methyl]cyclohexyl]carbonylamino]pent-4-enoyl]amino]hexan-2-yl]carbamoylamino]pentanedioic acid, ... (12 entities in total)
• Functional Keywords: glutamate carboxypeptidase ii (gcpii); naaladase; prostate-specific membrane antigen; inhibitor, hydrolase
• Biological source: Homo sapiens (human)
• Total number of polymer chains: 1
• Total formula weight: 84545.61

Authors

Motlova, L.,Barinka, C.,Benesova, M. (deposition date: 2022-11-15, release date: 2023-11-29, Last modification date: 2024-10-16)

• Primary citation: Motlova, L.,Barinka, C.,Benesova, M.; X-ray structure of human glutamate carboxypeptidase II (GCPII) in complex with an inhibitor P17; To Be Published,

Experimental method

X-RAY DIFFRACTION (1.55 Å)