8BLJ

Crystal structure of the ligand-binding domain (LBD) of human iGluR Delta-1 (GluD1), apo state

8BLJ の概要

• エントリーDOI: 10.2210/pdb8blj/pdb
• 分子名称: Glutamate receptor ionotropic, delta-1,Isoform 2 of Glutamate receptor ionotropic, delta-1, CALCIUM ION, CHLORIDE ION, ... (6 entities in total)
• 機能のキーワード: ion channel, ligand binding domain, glutamate receptor, apo state, membrane protein
• 由来する生物種: Homo sapiens (human); 詳細
• タンパク質・核酸の鎖数: 6
• 化学式量合計: 190091.96

構造登録者

Heroven, C.,Malinauskas, T.,Aricescu, A.R. (登録日: 2022-11-09, 公開日: 2023-11-22, 最終更新日: 2024-01-03)

• 主引用文献: Piot, L.,Heroven, C.,Bossi, S.,Zamith, J.,Malinauskas, T.,Johnson, C.,Wennagel, D.,Stroebel, D.,Charrier, C.,Aricescu, A.R.,Mony, L.,Paoletti, P.; GluD1 binds GABA and controls inhibitory plasticity.; Science, 382:1389-1394, 2023; PubMed: 38060673; DOI: 10.1126/science.adf3406

実験手法

X-RAY DIFFRACTION (2.18 Å)