8BK0

Crystal structure of human Ephrin type-A receptor 2 (EPHA2) Kinase domain in complex with LDN-211904

Summary for 8BK0

• Entry DOI: 10.2210/pdb8bk0/pdb
• Descriptor: Ephrin type-A receptor 2, 1,2-ETHANEDIOL, ~{N}-(2-chlorophenyl)-6-piperidin-4-yl-imidazo[1,2-a]pyridine-3-carboxamide, ... (4 entities in total)
• Functional Keywords: epha2, eck, typ i inhibitor, transferase
• Biological source: Homo sapiens (human)
• Total number of polymer chains: 1
• Total formula weight: 35314.22

Authors

Zhubi, R.,Gerninghaus, J.,Knapp, S.,Kraemer, A.,Structural Genomics Consortium (SGC) (deposition date: 2022-11-08, release date: 2022-11-16, Last modification date: 2024-01-31)

• Primary citation: Zhubi, R.,Gerninghaus, J.,Knapp, S.,Kraemer, A.,Structural Genomics Consortium (SGC); Crystal structure of human Ephrin type-A receptor 2 (EPHA2) Kinase domain in complex with LDN-211904; To Be Published,

Experimental method

X-RAY DIFFRACTION (1.7 Å)