8BJ5

Imine Reductase IR007 from Amycolatopsis azurea

Summary for 8BJ5

Entry DOI	10.2210/pdb8bj5/pdb
Descriptor	Imine Reductase, NADP NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE (3 entities in total)
Functional Keywords	amine, imine nadph, biocatalyst, oxidoreductase
Biological source	Amycolatopsis azurea
Total number of polymer chains	4
Total formula weight	126942.52
Authors	Gilio, A.K.,Steflik, J.,Grogan, G. (deposition date: 2022-11-03, release date: 2023-09-20)
Primary citation	Steflik, J.,Gilio, A.,Burns, M.,Grogan, G.,Kumar, R.,Lewis, R.,Martinez, C. Engineering of a Reductive Aminase to Enable the Synthesis of a Key Intermediate to a CDK 2/4/6 Inhibitor Acs Catalysis, 13:10065-10075, 2023 Cited by DOI: 10.1021/acscatal.3c01534 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (2.72 Å)

Structure validation