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8BJ5

Imine Reductase IR007 from Amycolatopsis azurea

Summary for 8BJ5
Entry DOI10.2210/pdb8bj5/pdb
DescriptorImine Reductase, NADP NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE (3 entities in total)
Functional Keywordsamine, imine nadph, biocatalyst, oxidoreductase
Biological sourceAmycolatopsis azurea
Total number of polymer chains4
Total formula weight126942.52
Authors
Gilio, A.K.,Steflik, J.,Grogan, G. (deposition date: 2022-11-03, release date: 2023-09-20)
Primary citationSteflik, J.,Gilio, A.,Burns, M.,Grogan, G.,Kumar, R.,Lewis, R.,Martinez, C.
Engineering of a Reductive Aminase to Enable the Synthesis of a Key Intermediate to a CDK 2/4/6 Inhibitor
Acs Catalysis, 13:10065-10075, 2023
Cited by
DOI: 10.1021/acscatal.3c01534
PDB entries with the same primary citation
Experimental method
X-RAY DIFFRACTION (2.72 Å)
Structure validation

221716

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