8BIS
Crystal structure of cystathionine gamma-lyase from Toxoplasma gondii in complex with DL-propargylglycine
Summary for 8BIS
Entry DOI | 10.2210/pdb8bis/pdb |
Descriptor | Cystathionine beta-lyase, putative, PYRIDOXAL-5'-PHOSPHATE, (2S)-2-aminopent-4-enoic acid, ... (4 entities in total) |
Functional Keywords | transsulfuration pathway, hydrogen sulfide, propargylglgycine, cystathionine gamma-lyase, cytosolic protein |
Biological source | Toxoplasma gondii |
Total number of polymer chains | 2 |
Total formula weight | 92572.45 |
Authors | Fernandez-Rodriguez, C.,Conter, C.,Oyenarte, I.,Favretto, F.,Quintana, I.,Martinez-Chantar, M.L.,Astegno, A.,Martinez-Cruz, L.A. (deposition date: 2022-11-02, release date: 2023-04-12, Last modification date: 2024-02-07) |
Primary citation | Fernandez-Rodriguez, C.,Conter, C.,Oyenarte, I.,Favretto, F.,Quintana, I.,Martinez-Chantar, M.L.,Astegno, A.,Martinez-Cruz, L.A. Structural basis of the inhibition of cystathionine gamma-lyase from Toxoplasma gondii by propargylglycine and cysteine. Protein Sci., 32:e4619-e4619, 2023 Cited by PubMed: 36883335DOI: 10.1002/pro.4619 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (2.266 Å) |
Structure validation
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