Loading
PDBj
MenuPDBj@FacebookPDBj@TwitterPDBj@YouTubewwPDB FoundationwwPDB
RCSB PDBPDBeBMRBAdv. SearchSearch help

8BIS

Crystal structure of cystathionine gamma-lyase from Toxoplasma gondii in complex with DL-propargylglycine

Summary for 8BIS
Entry DOI10.2210/pdb8bis/pdb
DescriptorCystathionine beta-lyase, putative, PYRIDOXAL-5'-PHOSPHATE, (2S)-2-aminopent-4-enoic acid, ... (4 entities in total)
Functional Keywordstranssulfuration pathway, hydrogen sulfide, propargylglgycine, cystathionine gamma-lyase, cytosolic protein
Biological sourceToxoplasma gondii
Total number of polymer chains2
Total formula weight92572.45
Authors
Fernandez-Rodriguez, C.,Conter, C.,Oyenarte, I.,Favretto, F.,Quintana, I.,Martinez-Chantar, M.L.,Astegno, A.,Martinez-Cruz, L.A. (deposition date: 2022-11-02, release date: 2023-04-12, Last modification date: 2024-02-07)
Primary citationFernandez-Rodriguez, C.,Conter, C.,Oyenarte, I.,Favretto, F.,Quintana, I.,Martinez-Chantar, M.L.,Astegno, A.,Martinez-Cruz, L.A.
Structural basis of the inhibition of cystathionine gamma-lyase from Toxoplasma gondii by propargylglycine and cysteine.
Protein Sci., 32:e4619-e4619, 2023
Cited by
PubMed: 36883335
DOI: 10.1002/pro.4619
PDB entries with the same primary citation
Experimental method
X-RAY DIFFRACTION (2.266 Å)
Structure validation

219140

PDB entries from 2024-05-01

PDB statisticsPDBj update infoContact PDBjnumon