8BI6

Crystal structure of human Choline Kinase A in complex with UNC0638

8BI6 の概要

• エントリーDOI: 10.2210/pdb8bi6/pdb
• 分子名称: Choline kinase alpha, MAGNESIUM ION, 2-cyclohexyl-6-methoxy-N-[1-(1-methylethyl)piperidin-4-yl]-7-(3-pyrrolidin-1-ylpropoxy)quinazolin-4-amine, ... (9 entities in total)
• 機能のキーワード: inhibitor, structural genomics, structural genomics consortium, sgc
• 由来する生物種: Homo sapiens (human)
• タンパク質・核酸の鎖数: 2
• 化学式量合計: 107253.29

構造登録者

Diaz-Saez, L.,Ward, J.,Kennedy, E.,von Delft, F.,Arrowsmith, C.H.,Edwards, A.M.,Bountra, C.,Huber, K.,Structural Genomics Consortium (SGC) (登録日: 2022-11-01, 公開日: 2023-11-15, 最終更新日: 2026-03-04)

• 主引用文献: Diaz-Saez, L.,Kennedy, E.,von Delft, F.,Knapp, S.,Arrowsmith, C.H.,Edwards, A.M.,Bountra, C.,Huber, K.; Crystal structure of human Choline Kinase A in complex with UNC0638; To Be Published,

実験手法

X-RAY DIFFRACTION (2.4 Å)