8BI5

Crystal structure of human Choline Kinase A in complex with UNC0737

Summary for 8BI5

• Entry DOI: 10.2210/pdb8bi5/pdb
• Descriptor: Choline kinase alpha, MAGNESIUM ION, 2-cyclohexyl-6-methoxy-~{N}-methyl-~{N}-(1-propan-2-ylpiperidin-4-yl)-7-(3-pyrrolidin-1-ylpropoxy)quinazolin-4-amine, ... (7 entities in total)
• Functional Keywords: inhibitor, structural genomics, structural genomics consortium, sgc
• Biological source: Homo sapiens (human)
• Total number of polymer chains: 2
• Total formula weight: 106800.72

Authors

Diaz-Saez, L.,Ward, J.,Kennedy, E.,von Delft, F.,Arrowsmith, C.H.,Edwards, A.M.,Bountra, C.,Huber, K.,Structural Genomics Consortium (SGC) (deposition date: 2022-11-01, release date: 2023-11-15)

• Primary citation: Diaz-Saez, L.,Kennedy, E.,von Delf, F.,Knapp, S.,Arrowsmith, C.H.,Edwards, A.M.,Bountra, C.,Huber, K.; Crystal structure of human Choline Kinase A in complex with UNC0737; To Be Published,

Experimental method

X-RAY DIFFRACTION (2.5 Å)