8BGD
Structure of Mpro from SARS-CoV-2 in complex with FGA147
Summary for 8BGD
Entry DOI | 10.2210/pdb8bgd/pdb |
Descriptor | 3C-like proteinase nsp5, (phenylmethyl) N-[(2S)-4-methyl-1-[[(2S)-4-nitro-1-[(3R)-2-oxidanylidenepyrrolidin-3-yl]butan-2-yl]amino]-1-oxidanylidene-pentan-2-yl]carbamate (3 entities in total) |
Functional Keywords | mpro, sars-cov-2, fga147, viral protein |
Biological source | Severe acute respiratory syndrome coronavirus 2 |
Total number of polymer chains | 1 |
Total formula weight | 34274.06 |
Authors | Medrano, F.J.,Romero, A. (deposition date: 2022-10-27, release date: 2023-11-08, Last modification date: 2024-10-09) |
Primary citation | Medrano, F.J.,Romero, A. Peptidyl Nitroalkenes Inhibit SARS-CoV-2 Main Protease and Block Virus Replication To Be Published, |
Experimental method | X-RAY DIFFRACTION (1.621 Å) |
Structure validation
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