8BG2

Crystal structure of the SARS-CoV-2 S RBD in complex with pT1580 scFV

8BG2 の概要

• エントリーDOI: 10.2210/pdb8bg2/pdb
• 分子名称: pT1375 single-chain Fv, Spike protein S1, 2-acetamido-2-deoxy-beta-D-glucopyranose, ... (4 entities in total)
• 機能のキーワード: protein binding/immune system, protein binding
• 由来する生物種: Homo sapiens; 詳細
• タンパク質・核酸の鎖数: 4
• 化学式量合計: 97928.35

構造登録者

Hansen, G.,Ssebyatika, G.L.,Krey, T. (登録日: 2022-10-27, 公開日: 2023-11-08)

• 主引用文献: Stein, C.S.,Hansen, G.,Ssebyatika, G.L.,Stroeh, L.,Benecke, T.,Menz, S.,Waldmann, J.-Y.,Vollmer, B.,Tipp, S.,Ochulor, O.,Herold, E.,Schwarzloh, B.,Mutschall, D.,Zischke, J.-Y.,Cordes, A.,Puppe, W.,Schneider, T.,Hinrichs, I.,Blasczyk, R.,Kleine-Weber, H.,Hoffmann, M.,Hoeper, M.,Kaiser, F.K.,Gonzalez-Hernandez, M.,Armando, F.K.,Ciurkiewicz, M.,Beythien, G.,Poehlmann, S.,Baumgaertner, W.,Gruenewald, K.,Osterhaus, A.,Schulz, T.,Krey, T.; Activity of broadly neutralizing antibodies against sarbecoviruses: a trade-off between SARS-CoV-2 variants and distant coronaviruses?; To be published,

実験手法

X-RAY DIFFRACTION (2.1 Å)