8BC7
Cereblon isoform 4 from Magnetospirillum gryphiswaldense in complex an aminoglutarimide degron peptide
Summary for 8BC7
| Entry DOI | 10.2210/pdb8bc7/pdb |
| Descriptor | Cereblon isoform 4, PHE-PHE-GLU-GLN-MET-GLN-QCI, ZINC ION, ... (5 entities in total) |
| Functional Keywords | protein damage, protein ageing, protein chain break, aminoglutarimide, signaling protein |
| Biological source | Magnetospirillum gryphiswaldense More |
| Total number of polymer chains | 4 |
| Total formula weight | 42678.41 |
| Authors | Heim, C.,Albrecht, R.,Spring, A.K.,Hartmann, M.D. (deposition date: 2022-10-15, release date: 2023-01-11, Last modification date: 2024-02-07) |
| Primary citation | Heim, C.,Spring, A.K.,Kirchgassner, S.,Schwarzer, D.,Hartmann, M.D. Identification and structural basis of C-terminal cyclic imides as natural degrons for cereblon. Biochem.Biophys.Res.Commun., 637:66-72, 2022 Cited by PubMed: 36375252DOI: 10.1016/j.bbrc.2022.11.001 PDB entries with the same primary citation |
| Experimental method | X-RAY DIFFRACTION (1.719 Å) |
Structure validation
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