8BC6

Cereblon isoform 4 from Magnetospirillum gryphiswaldense in complex an aspartimide degron peptide

Summary for 8BC6

Entry DOI	10.2210/pdb8bc6/pdb
Descriptor	Cereblon isoform 4, GLN-MET-GLN-SNN, ZINC ION, ... (5 entities in total)
Functional Keywords	protein damage, protein ageing, protein chain break, aspartimide, signaling protein
Biological source	Magnetospirillum gryphiswaldense More
Total number of polymer chains	5
Total formula weight	42571.69
Authors	Heim, C.,Hartmann, M.D. (deposition date: 2022-10-15, release date: 2023-01-11, Last modification date: 2023-11-15)
Primary citation	Heim, C.,Spring, A.K.,Kirchgassner, S.,Schwarzer, D.,Hartmann, M.D. Identification and structural basis of C-terminal cyclic imides as natural degrons for cereblon. Biochem.Biophys.Res.Commun., 637:66-72, 2022 Cited by PubMed: 36375252 DOI: 10.1016/j.bbrc.2022.11.001 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (1.72 Å)

Structure validation