8B9U
Structure of ClpC1 NTD from Mycobacterium tuberculosis
Summary for 8B9U
Entry DOI | 10.2210/pdb8b9u/pdb |
Descriptor | ATP-dependent Clp protease ATP-binding subunit ClpC1, (MLE)V(MAA)(E9M)G, FORMIC ACID, ... (4 entities in total) |
Functional Keywords | ligand bound state, chaperone |
Biological source | Mycobacterium tuberculosis (strain ATCC 25618 / H37Rv) More |
Total number of polymer chains | 3 |
Total formula weight | 32587.36 |
Authors | Meinhart, A.,Hoi, D.M.,Clausen, T. (deposition date: 2022-10-10, release date: 2023-07-05, Last modification date: 2024-02-07) |
Primary citation | Hoi, D.M.,Junker, S.,Junk, L.,Schwechel, K.,Fischel, K.,Podlesainski, D.,Hawkins, P.M.E.,van Geelen, L.,Kaschani, F.,Leodolter, J.,Morreale, F.E.,Kleine, S.,Guha, S.,Rumpel, K.,Schmiedel, V.M.,Weinstabl, H.,Meinhart, A.,Payne, R.J.,Kaiser, M.,Hartl, M.,Boehmelt, G.,Kazmaier, U.,Kalscheuer, R.,Clausen, T. Clp-targeting BacPROTACs impair mycobacterial proteostasis and survival. Cell, 186:2176-, 2023 Cited by PubMed: 37137307DOI: 10.1016/j.cell.2023.04.009 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (2.25 Å) |
Structure validation
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