8B6R
X-ray structure of the haloalkane dehalogenase HaloTag7 labeled with a chloroalkane Cyanine3 fluorophore substrate
Summary for 8B6R
Entry DOI | 10.2210/pdb8b6r/pdb |
Related | 8B6S 8B6T |
Descriptor | Haloalkane dehalogenase, ~{N}-[2-[2-(6-chloranylhexoxy)ethoxy]ethyl]-6-[3,3-dimethyl-2-[(~{E})-3-(1,3,3-trimethylindol-2-ylidene)prop-1-enyl]indol-1-ium-1-yl]hexanamide, CHLORIDE ION, ... (6 entities in total) |
Functional Keywords | haloalkane dehalogenase, halotag, halotag7, self-labeling protein, fluorophore, cyanine 3, cy3, hydrolase |
Biological source | Rhodococcus sp. |
Total number of polymer chains | 1 |
Total formula weight | 34317.47 |
Authors | Tarnawski, M.,Hellweg, L.,Hiblot, J. (deposition date: 2022-09-27, release date: 2023-07-26, Last modification date: 2023-09-06) |
Primary citation | Hellweg, L.,Edenhofer, A.,Barck, L.,Huppertz, M.C.,Frei, M.S.,Tarnawski, M.,Bergner, A.,Koch, B.,Johnsson, K.,Hiblot, J. A general method for the development of multicolor biosensors with large dynamic ranges. Nat.Chem.Biol., 19:1147-1157, 2023 Cited by PubMed: 37291200DOI: 10.1038/s41589-023-01350-1 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (1.5 Å) |
Structure validation
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