8B6R

X-ray structure of the haloalkane dehalogenase HaloTag7 labeled with a chloroalkane Cyanine3 fluorophore substrate

8B6R の概要

• エントリーDOI: 10.2210/pdb8b6r/pdb
• 関連するPDBエントリー: 8B6S 8B6T
• 分子名称: Haloalkane dehalogenase, ~{N}-[2-[2-(6-chloranylhexoxy)ethoxy]ethyl]-6-[3,3-dimethyl-2-[(~{E})-3-(1,3,3-trimethylindol-2-ylidene)prop-1-enyl]indol-1-ium-1-yl]hexanamide, CHLORIDE ION, ... (6 entities in total)
• 機能のキーワード: haloalkane dehalogenase, halotag, halotag7, self-labeling protein, fluorophore, cyanine 3, cy3, hydrolase
• 由来する生物種: Rhodococcus sp.
• タンパク質・核酸の鎖数: 1
• 化学式量合計: 34317.47

構造登録者

Tarnawski, M.,Hellweg, L.,Hiblot, J. (登録日: 2022-09-27, 公開日: 2023-07-26, 最終更新日: 2023-09-06)

• 主引用文献: Hellweg, L.,Edenhofer, A.,Barck, L.,Huppertz, M.C.,Frei, M.S.,Tarnawski, M.,Bergner, A.,Koch, B.,Johnsson, K.,Hiblot, J.; A general method for the development of multicolor biosensors with large dynamic ranges.; Nat.Chem.Biol., 19:1147-1157, 2023; PubMed: 37291200; DOI: 10.1038/s41589-023-01350-1

実験手法

X-RAY DIFFRACTION (1.5 Å)