8B6C
Cryo-EM structure of ribosome-Sec61 in complex with cyclotriazadisulfonamide derivative CK147
This is a non-PDB format compatible entry.
Summary for 8B6C
Entry DOI | 10.2210/pdb8b6c/pdb |
Related | 8B5L |
EMDB information | 15863 |
Descriptor | 60S ribosomal protein L21, 60S ribosomal protein L7a, 60S ribosomal protein L11, ... (50 entities in total) |
Functional Keywords | ribosome, sec61, trap, translocon, translation, rna binding protein, eef2, ck147, cada, translocon inhibitor, 80s, 60s, 40s, cyclotriazadisulfonamide, membrane protein |
Biological source | Oryctolagus cuniculus (rabbit) More |
Total number of polymer chains | 47 |
Total formula weight | 2505605.89 |
Authors | Pauwels, E.,Shewakramani, N.R.,De Wijngaert, B.,Vermeire, K.,Das, K. (deposition date: 2022-09-26, release date: 2023-02-22, Last modification date: 2023-03-15) |
Primary citation | Pauwels, E.,Shewakramani, N.R.,De Wijngaert, B.,Camps, A.,Provinciael, B.,Stroobants, J.,Kalies, K.U.,Hartmann, E.,Maes, P.,Vermeire, K.,Das, K. Structural insights into TRAP association with ribosome-Sec61 complex and translocon inhibition by a CADA derivative. Sci Adv, 9:eadf0797-eadf0797, 2023 Cited by PubMed: 36867692DOI: 10.1126/sciadv.adf0797 PDB entries with the same primary citation |
Experimental method | ELECTRON MICROSCOPY (2.79 Å) |
Structure validation
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