8B2J

Crystal structure of human STING in complex with ADU-S100

Summary for 8B2J

• Entry DOI: 10.2210/pdb8b2j/pdb
• Descriptor: Stimulator of interferon genes protein, (1~{R},3~{S},6~{R},8~{R},9~{R},10~{S},12~{S},15~{R},17~{R},18~{R})-8,17-bis(6-aminopurin-9-yl)-3,12-bis(oxidanylidene)-3,12-bis(sulfanyl)-2,4,7,11,13,16-hexaoxa-3$l^{5},12$l^{5}-diphosphatricyclo[13.2.1.0^{6,10}]octadecane-9,18-diol, CALCIUM ION, ... (5 entities in total)
• Functional Keywords: stimulator of interferon protein, immune system
• Biological source: Homo sapiens (human)
• Total number of polymer chains: 2
• Total formula weight: 55315.91

Authors

Nawrotek, A.,Vuillard, L.,Miallau, L. (deposition date: 2022-09-14, release date: 2022-11-30, Last modification date: 2024-05-01)

• Primary citation: Nawrotek, A.,Vuillard, L.,Miallau, L.; Crystal structure of human STING in complex with ADU-S100; To Be Published,

Experimental method

X-RAY DIFFRACTION (2.174 Å)