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8B0D

Crystal structure of beta-glucuronidase from Acidobacterium capsulatum in complex with covalent inhibitor VB151

This is a non-PDB format compatible entry.
Summary for 8B0D
Entry DOI10.2210/pdb8b0d/pdb
Descriptorbeta-glucuronidase from Acidobacterium capsulatum, ALANINE, (1~{S},2~{R},3~{R},4~{S},6~{S})-2-(2-acetamidoethoxy)-3,4,6-tris(oxidanyl)cyclohexane-1-carboxylic acid, ... (5 entities in total)
Functional Keywordsb-glucuronidase, hydrolase
Biological sourceAcidobacterium capsulatum
Total number of polymer chains1
Total formula weight51276.99
Authors
Armstrong, Z.,Davies, G.J. (deposition date: 2022-09-07, release date: 2022-12-28, Last modification date: 2024-02-07)
Primary citationBorlandelli, V.,Armstrong, Z.,Nin-Hill, A.,Codee, J.D.C.,Raich, L.,Artola, M.,Rovira, C.,Davies, G.J.,Overkleeft, H.S.
4-O-Substituted Glucuronic Cyclophellitols are Selective Mechanism-Based Heparanase Inhibitors.
Chemmedchem, 18:e202200580-e202200580, 2023
Cited by
PubMed: 36533564
DOI: 10.1002/cmdc.202200580
PDB entries with the same primary citation
Experimental method
X-RAY DIFFRACTION (1.62 Å)
Structure validation

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