8AUU

Human Aldose Reductase Mutant A299G in Complex with a Ligand with an IDD Structure ({5-fluoro-2-[(3-nitrobenzyl)carbamoyl]phenoxy}acetic acid)

8AUU の概要

• エントリーDOI: 10.2210/pdb8auu/pdb
• 分子名称: Aldo-keto reductase family 1 member B1, NADP NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE, {5-fluoro-2-[(3-nitrobenzyl)carbamoyl]phenoxy}acetic acid, ... (5 entities in total)
• 機能のキーワード: human aldose reductase, har, aldo-keto-reductase, a299g mutant, idd_06, nadp+, diabetes, oxidoreductase
• 由来する生物種: Homo sapiens (human)
• タンパク質・核酸の鎖数: 1
• 化学式量合計: 37168.12

構造登録者

Hubert, L.-S.,Heine, A.,Klebe, G. (登録日: 2022-08-25, 公開日: 2023-09-06)

• 主引用文献: Hubert, L.-S.,Heine, A.,Klebe, G.,Scheer, F.,Diederich, W.; Human Aldose Reductase Mutant A299G in Complex with a Ligand with an IDD Structure ({5-fluoro-2-[(3-nitrobenzyl)carbamoyl]phenoxy}acetic acid); To Be Published,

実験手法

X-RAY DIFFRACTION (0.95 Å)