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8ASE

Crystal structure of Thrombin in complex with macrocycle T3

Summary for 8ASE
Entry DOI10.2210/pdb8ase/pdb
DescriptorThrombin light chain, Thrombin heavy chain, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, ... (7 entities in total)
Functional Keywordsserine endopeptidases, alpha-thrombin, activated factor iia, fibrinogenase, hydrolase
Biological sourceHomo sapiens (human)
More
Total number of polymer chains4
Total formula weight69763.66
Authors
Chinellato, M.,Angelini, A.,Nielsen, A.,Heinis, C.,Cendron, L. (deposition date: 2022-08-19, release date: 2023-11-29)
Primary citationNielsen, A.,Chinellato, M.,Cendron, L.,Angelini, A.,Heinis, C.
Crystal structure of Thrombin in complex with optimized macrocycles T1 and T3
To Be Published,
Experimental method
X-RAY DIFFRACTION (2.55 Å)
Structure validation

218853

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