8AND

Domain swapped dimer of smolstatin (stefin) from Sphaerospora molnari

This is a non-PDB format compatible entry.

Summary for 8AND

• Entry DOI: 10.2210/pdb8and/pdb
• Descriptor: Smolstatin, 1,2-ETHANEDIOL (3 entities in total)
• Functional Keywords: cystatin superfamily, stefin, inhibitor from parasite, 3d domain swapped dimer, hydrolase inhibitor
• Biological source: Sphaerospora molnari
• Total number of polymer chains: 2
• Total formula weight: 23020.29

Authors

Havlickova, P.,Bartosova-Sojkova, P.,Sojka, D.,Kascakova, B.,Gavira, J.A.,Kuta Smatanova, I. (deposition date: 2022-08-05, release date: 2024-04-17, Last modification date: 2026-06-03)

• Primary citation: Bartosova-Sojkova, P.,Dobai, T.,Kyslik, J.,Havlickova, P.,Vancova, M.,Picard-Sanchez, M.A.,Qadiri, S.S.N.,Martins, L.A.,Urbanova, V.,Kosakyan, A.,Bily, T.,Kale, D.,Kotal, J.,Chan, J.T.H.,Korytar, T.,Ludwig, J.,Smatanova, I.K.,Holzer, A.S.,Sojka, D.; Smolstatin1, a unique cystatin-like stefin of Sphaerospora molnari, is essential for parasite development; Curr Res Microb Sci, :100611-, 2026; DOI: 10.1016/j.crmicr.2026.100611

Experimental method

X-RAY DIFFRACTION (1.991 Å)