8AEV

Human acetylcholinesterase in complex with N,N,N-trimethyl-2-oxo-2-(2-(pyridin-2-ylmethylene)hydrazineyl)ethan-1-aminium

8AEV の概要

• エントリーDOI: 10.2210/pdb8aev/pdb
• 関連するPDBエントリー: 8AEN
• 分子名称: Acetylcholinesterase, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-[alpha-L-fucopyranose-(1-6)]2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, ... (10 entities in total)
• 機能のキーワード: inhibitor, complex, zinc, acetylcholinesterase, hydrolase
• 由来する生物種: Homo sapiens (human)
• タンパク質・核酸の鎖数: 2
• 化学式量合計: 124979.21

構造登録者

Nachon, F.,Dias, J.,Brazzolotto, X. (登録日: 2022-07-13, 公開日: 2023-06-14, 最終更新日: 2024-02-07)

• 主引用文献: Nachon, F.,Brazzolotto, X.,Dias, J.,Courageux, C.,Drozdz, W.,Cao, X.Y.,Stefankiewicz, A.R.,Lehn, J.M.; Grid-Type Quaternary Metallosupramolecular Compounds Inhibit Human Cholinesterases through Dynamic Multivalent Interactions.; Chembiochem, 23:e202200456-e202200456, 2022; PubMed: 36193860; DOI: 10.1002/cbic.202200456

実験手法

X-RAY DIFFRACTION (2.89 Å)