8AE9

Human Aldose Reductase in Complex with a Hydroxyphenyl-Thiophen-Acid Inhibitor (Schl32357)

8AE9 の概要

• エントリーDOI: 10.2210/pdb8ae9/pdb
• 分子名称: Aldose reductase, NADP NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE, 5-(5-(3-hydroxyphenyl)thiophen-2-yl)pentanoic acid, ... (5 entities in total)
• 機能のキーワード: human aldose reductase, har, aldo-keto-reductase, schl32357 ligand, nadp+, diabetes, oxidoreductase
• 由来する生物種: Homo sapiens (human)
• タンパク質・核酸の鎖数: 1
• 化学式量合計: 36996.23

構造登録者

Hubert, L.-S.,Heine, A.,Klebe, G.,Reul, S. (登録日: 2022-07-12, 公開日: 2023-08-16)

• 主引用文献: Hubert, L.-S.,Heine, A.,Klebe, G.,Reul, S.; Human Aldose Reductase in Complex with a Hydroxyphenyl-Thiophen-Acid Inhibitor (Schl32357); To Be Published,

実験手法

X-RAY DIFFRACTION (0.95 Å)