8ADQ

Crystal structure of holo-SwHPA-Mg (hydroxy ketone aldolase) from Sphingomonas wittichii RW1 in complex with hydroxypyruvate and D-Glyceraldehyde

Summary for 8ADQ

Entry DOI	10.2210/pdb8adq/pdb
Descriptor	HpcH/HpaI aldolase, 3-HYDROXYPYRUVIC ACID, D-Glyceraldehyde, ... (8 entities in total)
Functional Keywords	hydroxy-keto aldolase; aldol condensation; aldol cleavage; stereospecificity; tim barrel fold, lyase
Biological source	Rhizorhabdus wittichii RW1
Total number of polymer chains	1
Total formula weight	28586.24
Authors	Justo, I.,Marsden, S.R.,Hanefeld, U.,Bento, I. (deposition date: 2022-07-11, release date: 2022-11-23, Last modification date: 2024-01-31)
Primary citation	Marsden, S.R.,Wijma, H.J.,Mohr, M.K.F.,Justo, I.,Hagedoorn, P.L.,Laustsen, J.,Jeffries, C.M.,Svergun, D.,Mestrom, L.,McMillan, D.G.G.,Bento, I.,Hanefeld, U. Substrate Induced Movement of the Metal Cofactor between Active and Resting State. Angew.Chem.Int.Ed.Engl., 61:e202213338-e202213338, 2022 Cited by PubMed: 36214476 DOI: 10.1002/anie.202213338 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (1.6 Å)

Structure validation