8ADF

X-ray crystal structure of PPAR gamma ligand binding domain in complex with CZ39

Summary for 8ADF

Entry DOI	10.2210/pdb8adf/pdb
Descriptor	Peroxisome proliferator-activated receptor gamma, (2R)-3-(4-bromophenyl)-2-(3-hydroxyphenyl)-4-oxidanyl-2H-furan-5-one (3 entities in total)
Functional Keywords	nuclear receptor, transcription
Biological source	Homo sapiens (human)
Total number of polymer chains	2
Total formula weight	69533.79
Authors	Capelli, D.,Montanari, R.,Pochetti, G.,Meneghetti, F.,Villa, S. (deposition date: 2022-07-08, release date: 2023-04-26, Last modification date: 2024-02-07)
Primary citation	Capelli, D.,Cazzaniga, G.,Mori, M.,Laghezza, A.,Loiodice, F.,Quaglia, M.,Negro, E.,Meneghetti, F.,Villa, S.,Montanari, R. Biological Screening and Crystallographic Studies of Hydroxy gamma-Lactone Derivatives to Investigate PPAR gamma Phosphorylation Inhibition. Biomolecules, 13:-, 2023 Cited by PubMed: 37189440 DOI: 10.3390/biom13040694 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (2.13 Å)

Structure validation