8ABS
Crystal structure of CYP109A2 from Bacillus megaterium bound with testosterone and putative ligand 4,6-dimethyloctanoic acid
Summary for 8ABS
Entry DOI | 10.2210/pdb8abs/pdb |
Descriptor | Cytochrome P450, HEME B/C, (4~{S},6~{S})-4,6-dimethyloctanoic acid, ... (6 entities in total) |
Functional Keywords | cytochrome p450, testosterone, fatty acid, steroid, complex, oxidoreductase |
Biological source | Priestia megaterium DSM 319 |
Total number of polymer chains | 1 |
Total formula weight | 48641.96 |
Authors | Jozwik, I.K.,Rozeboom, H.J.,Thunnissen, A.-M.W.H. (deposition date: 2022-07-04, release date: 2023-07-12, Last modification date: 2024-02-07) |
Primary citation | Jozwik, I.K.,Bombino, E.,Abdulmughni, A.,Hartz, P.,Rozeboom, H.J.,Wijma, H.J.,Kappl, R.,Janssen, D.B.,Bernhardt, R.,Thunnissen, A.W.H. Regio- and stereoselective steroid hydroxylation by CYP109A2 from Bacillus megaterium explored by X-ray crystallography and computational modeling. Febs J., 290:5016-5035, 2023 Cited by PubMed: 37453052DOI: 10.1111/febs.16906 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (1.75 Å) |
Structure validation
Download full validation report