8ABR

Crystal structure of CYP109A2 from Bacillus megaterium bound with putative ligands hexanoic acid and octanoic acid

Summary for 8ABR

Entry DOI	10.2210/pdb8abr/pdb
Descriptor	Cytochrome P450, HEME B/C, HEXANOIC ACID, ... (6 entities in total)
Functional Keywords	cytochrome p450 monooxygenase, complex, fatty acid, steroid hydroxylation, oxidoreductase
Biological source	Priestia megaterium DSM 319
Total number of polymer chains	1
Total formula weight	48441.64
Authors	Jozwik, I.K.,Rozeboom, H.J.,Thunnissen, A.-M.W.H. (deposition date: 2022-07-04, release date: 2023-07-12, Last modification date: 2024-02-07)
Primary citation	Jozwik, I.K.,Bombino, E.,Abdulmughni, A.,Hartz, P.,Rozeboom, H.J.,Wijma, H.J.,Kappl, R.,Janssen, D.B.,Bernhardt, R.,Thunnissen, A.W.H. Regio- and stereoselective steroid hydroxylation by CYP109A2 from Bacillus megaterium explored by X-ray crystallography and computational modeling. Febs J., 290:5016-5035, 2023 Cited by PubMed: 37453052 DOI: 10.1111/febs.16906 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (2.1 Å)

Structure validation