8AAN
The nucleoprotein complex of Rep protein with iteron containing dsDNA and DUE ssDNA.
Summary for 8AAN
Entry DOI | 10.2210/pdb8aan/pdb |
Descriptor | DNA (5'-D(*CP*CP*TP*GP*TP*GP*AP*CP*AP*AP*AP*TP*TP*GP*CP*CP*CP*TP*CP*AP*GP*T)-3'), DNA (5'-D(*CP*TP*GP*AP*GP*GP*GP*CP*AP*AP*TP*TP*TP*GP*TP*CP*AP*CP*AP*GP*GP*T)-3'), Replication initiation protein, ... (6 entities in total) |
Functional Keywords | replication initiation protein nucleoprotein complex nucleic acid binding dna binding, dna binding protein |
Biological source | Escherichia coli More |
Total number of polymer chains | 4 |
Total formula weight | 45269.17 |
Authors | Nowacka, M.,Wegrzyn, K. (deposition date: 2022-07-01, release date: 2023-09-27, Last modification date: 2023-11-08) |
Primary citation | Wegrzyn, K.,Oliwa, M.,Nowacka, M.,Zabrocka, E.,Bury, K.,Purzycki, P.,Czaplewska, P.,Pipka, J.,Giraldo, R.,Konieczny, I. Rep protein accommodates together dsDNA and ssDNA which enables a loop-back mechanism to plasmid DNA replication initiation. Nucleic Acids Res., 51:10551-10567, 2023 Cited by PubMed: 37713613DOI: 10.1093/nar/gkad740 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (2.19 Å) |
Structure validation
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