8A99

SARS Cov2 Spike in 1-up conformation complex with Fab47

Summary for 8A99

Entry DOI	10.2210/pdb8a99/pdb
EMDB information	15273
Descriptor	SARS-CoV2 spike 1-up conformation in complex with Fab47, Fab47 (Heavy chain variable domain), Fab47 (Light chain Variable domain), ... (5 entities in total)
Functional Keywords	spike, antibody, viral protein
Biological source	Severe acute respiratory syndrome coronavirus 2 More
Total number of polymer chains	9
Total formula weight	515070.42
Authors	Hallberg, B.M.,Das, H. (deposition date: 2022-06-28, release date: 2023-05-10, Last modification date: 2023-09-27)
Primary citation	Pushparaj, P.,Nicoletto, A.,Sheward, D.J.,Das, H.,Castro Dopico, X.,Perez Vidakovics, L.,Hanke, L.,Chernyshev, M.,Narang, S.,Kim, S.,Fischbach, J.,Ekstrom, S.,McInerney, G.,Hallberg, B.M.,Murrell, B.,Corcoran, M.,Karlsson Hedestam, G.B. Immunoglobulin germline gene polymorphisms influence the function of SARS-CoV-2 neutralizing antibodies. Immunity, 56:193-206.e7, 2023 Cited by PubMed: 36574772 DOI: 10.1016/j.immuni.2022.12.005 PDB entries with the same primary citation
Experimental method	ELECTRON MICROSCOPY (2.5 Å)

Structure validation