8A6I
Structure of the low complexity domain of TDP-43 (fragment 309-350) with methionine sulfoxide modifications
Summary for 8A6I
Entry DOI | 10.2210/pdb8a6i/pdb |
NMR Information | BMRB: 34737 |
Descriptor | TAR DNA-binding protein 43 (1 entity in total) |
Functional Keywords | tdp-43, low complexity domain, prion-like domain, methionine sulfoxide, llps, unknown function |
Biological source | Homo sapiens (human) |
Total number of polymer chains | 1 |
Total formula weight | 4331.80 |
Authors | Carrasco, J.,Anton, R.,Pantoja-Uceda, D.,Laurents, D.V.,Oroz, J. (deposition date: 2022-06-17, release date: 2023-02-08) |
Primary citation | Carrasco, J.,Anton, R.,Valbuena, A.,Pantoja-Uceda, D.,Mukhi, M.,Hervas, R.,Laurents, D.V.,Gasset, M.,Oroz, J. Metamorphism in TDP-43 prion-like domain determines chaperone recognition. Nat Commun, 14:466-466, 2023 Cited by PubMed: 36709343DOI: 10.1038/s41467-023-36023-z PDB entries with the same primary citation |
Experimental method | SOLUTION NMR |
Structure validation
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