8A6I

Structure of the low complexity domain of TDP-43 (fragment 309-350) with methionine sulfoxide modifications

Summary for 8A6I

Entry DOI	10.2210/pdb8a6i/pdb
NMR Information	BMRB: 34737
Descriptor	TAR DNA-binding protein 43 (1 entity in total)
Functional Keywords	tdp-43, low complexity domain, prion-like domain, methionine sulfoxide, llps, unknown function
Biological source	Homo sapiens (human)
Total number of polymer chains	1
Total formula weight	4331.80
Authors	Carrasco, J.,Anton, R.,Pantoja-Uceda, D.,Laurents, D.V.,Oroz, J. (deposition date: 2022-06-17, release date: 2023-02-08)
Primary citation	Carrasco, J.,Anton, R.,Valbuena, A.,Pantoja-Uceda, D.,Mukhi, M.,Hervas, R.,Laurents, D.V.,Gasset, M.,Oroz, J. Metamorphism in TDP-43 prion-like domain determines chaperone recognition. Nat Commun, 14:466-466, 2023 Cited by PubMed: 36709343 DOI: 10.1038/s41467-023-36023-z PDB entries with the same primary citation
Experimental method	SOLUTION NMR

Structure validation