8A67

Branched Lys48- and Lys63-linked tri-ubiquitin (K48-K63-Ub3) in complex with matured synthetic nanobody NbSL3.3Q (3rd generation)

Summary for 8A67

• Entry DOI: 10.2210/pdb8a67/pdb
• Related: 7NBB 7NPO
• Descriptor: Polyubiquitin-B, Synthetic Nanobody NbSL3.3Q, GLYCEROL, ... (9 entities in total)
• Functional Keywords: branched ubiquitin, nanobody, complex, signaling protein
• Biological source: Homo sapiens (human); More
• Total number of polymer chains: 8
• Total formula weight: 83368.64

Authors

Lange, S.M.,Kulathu, Y. (deposition date: 2022-06-16, release date: 2023-02-15, Last modification date: 2024-07-31)

• Primary citation: Lange, S.M.,McFarland, M.R.,Lamoliatte, F.,Carroll, T.,Krshnan, L.,Perez-Rafols, A.,Kwasna, D.,Shen, L.,Wallace, I.,Cole, I.,Armstrong, L.A.,Knebel, A.,Johnson, C.,De Cesare, V.,Kulathu, Y.; VCP/p97-associated proteins are binders and debranching enzymes of K48-K63-branched ubiquitin chains.; Nat.Struct.Mol.Biol., 2024; PubMed: 38977901; DOI: 10.1038/s41594-024-01354-y

Experimental method

X-RAY DIFFRACTION (1.86 Å)