8A4Y
SARS-CoV-2 non-structural protein-1 (nsp1) in complex with N-(2,3-dihydro-1H-inden-5-yl)acetamide
Summary for 8A4Y
| Entry DOI | 10.2210/pdb8a4y/pdb |
| Descriptor | Host translation inhibitor nsp1, N-(2,3-dihydro-1H-inden-5-yl)acetamide (3 entities in total) |
| Functional Keywords | sars-cov-2, non-structural protein-1, fragment hit, complex, viral protein |
| Biological source | Severe acute respiratory syndrome coronavirus 2 |
| Total number of polymer chains | 1 |
| Total formula weight | 13284.38 |
| Authors | Borsatto, A.,Galdadas, I.,Ma, S.,Damfo, S.,Haider, S.,Kozielski, F.,Estarellas, C.,Gervasio, F.L. (deposition date: 2022-06-13, release date: 2022-11-23, Last modification date: 2024-01-31) |
| Primary citation | Borsatto, A.,Akkad, O.,Galdadas, I.,Ma, S.,Damfo, S.,Haider, S.,Kozielski, F.,Estarellas, C.,Gervasio, F.L. Revealing druggable cryptic pockets in the Nsp1 of SARS-CoV-2 and other beta-coronaviruses by simulations and crystallography. Elife, 11:-, 2022 Cited by PubMed: 36412088DOI: 10.7554/eLife.81167 PDB entries with the same primary citation |
| Experimental method | X-RAY DIFFRACTION (1.099 Å) |
Structure validation
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