8A49

Endoglycosidase S in complex with IgG1 Fc

8A49 の概要

• エントリーDOI: 10.2210/pdb8a49/pdb
• 分子名称: IgG1 Fc, Secreted endoglycosidase EndoS, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-2)-alpha-D-mannopyranose-(1-3)-[2-acetamido-2-deoxy-beta-D-glucopyranose-(1-2)-alpha-D-mannopyranose-(1-6)]beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-[alpha-L-fucopyranose-(1-6)]2-acetamido-2-deoxy-beta-D-glucopyranose, ... (4 entities in total)
• 機能のキーワード: endoglycosidase, antibody, complex, immune system
• 由来する生物種: Homo sapiens; 詳細
• タンパク質・核酸の鎖数: 4
• 化学式量合計: 257490.20

構造登録者

Sudol, A.S.L.,Tews, I.,Crispin, M. (登録日: 2022-06-10, 公開日: 2022-11-30, 最終更新日: 2024-01-31)

• 主引用文献: Sudol, A.S.L.,Butler, J.,Ivory, D.P.,Tews, I.,Crispin, M.; Extensive substrate recognition by the streptococcal antibody-degrading enzymes IdeS and EndoS.; Nat Commun, 13:7801-7801, 2022; PubMed: 36528711; DOI: 10.1038/s41467-022-35340-z

実験手法

X-RAY DIFFRACTION (3.45 Å)