8A48

Less crystallisable" IgG1 Fc fragment (E382S variant)

8A48 の概要

• エントリーDOI: 10.2210/pdb8a48/pdb
• 分子名称: IgG1 Fc, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-2)-alpha-D-mannopyranose-(1-6)-[alpha-D-mannopyranose-(1-3)]beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-[alpha-L-fucopyranose-(1-6)]2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-2)-alpha-D-mannopyranose-(1-3)-[2-acetamido-2-deoxy-beta-D-glucopyranose-(1-2)-alpha-D-mannopyranose-(1-6)]beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-[alpha-L-fucopyranose-(1-6)]2-acetamido-2-deoxy-beta-D-glucopyranose, ... (5 entities in total)
• 機能のキーワード: antibody, igg, fc, fragment crystallisable, immune system
• 由来する生物種: Homo sapiens (human)
• タンパク質・核酸の鎖数: 2
• 化学式量合計: 53961.53

構造登録者

Sudol, A.S.L.,Tews, I.,Crispin, M. (登録日: 2022-06-10, 公開日: 2022-11-30, 最終更新日: 2024-01-31)

• 主引用文献: Sudol, A.S.L.,Butler, J.,Ivory, D.P.,Tews, I.,Crispin, M.; Extensive substrate recognition by the streptococcal antibody-degrading enzymes IdeS and EndoS.; Nat Commun, 13:7801-7801, 2022; PubMed: 36528711; DOI: 10.1038/s41467-022-35340-z

実験手法

X-RAY DIFFRACTION (3.044 Å)