8A40
Structure of mammalian Pol II-TFIIS elongation complex
Summary for 8A40
Entry DOI | 10.2210/pdb8a40/pdb |
EMDB information | 15129 |
Descriptor | DNA-directed RNA polymerase subunit, DNA-directed RNA polymerases I, II, and III subunit RPABC5, DNA-directed RNA polymerase II subunit RPB11-a, ... (18 entities in total) |
Functional Keywords | chromatin, rna polymerase ii, nucleosome, tfiis, transcription, elongation |
Biological source | Homo sapiens (human) More |
Total number of polymer chains | 16 |
Total formula weight | 594086.32 |
Authors | Farnung, L.,Ochmann, M.,Garg, G.,Vos, S.M.,Cramer, P. (deposition date: 2022-06-09, release date: 2023-08-23, Last modification date: 2024-06-12) |
Primary citation | Farnung, L.,Ochmann, M.,Garg, G.,Vos, S.M.,Cramer, P. Structure of a backtracked hexasomal intermediate of nucleosome transcription. Mol.Cell, 82:3126-3134.e7, 2022 Cited by PubMed: 35858621DOI: 10.1016/j.molcel.2022.06.027 PDB entries with the same primary citation |
Experimental method | ELECTRON MICROSCOPY (3 Å) |
Structure validation
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