8A3N

Geissoschizine synthase from Catharanthus roseus - binary complex with NADP+

Summary for 8A3N

Entry DOI	10.2210/pdb8a3n/pdb
Descriptor	Geissoschizine synthase, NADP NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE, ZINC ION, ... (4 entities in total)
Functional Keywords	medium-chain alcohol dehydrogenase, oxidoreductase, iminium reduction, natural product biosynthesis
Biological source	Catharanthus roseus (Madagascar periwinkle)
Total number of polymer chains	2
Total formula weight	80923.59
Authors	Langley, C.,Tatsis, E.,Hong, B.,Nakamura, Y.,Kamileen, M.O.,Paetz, C.,Stevenson, C.E.M.,Basquin, J.,Lawson, D.M.,Caputi, L.,O'Connor, S.E. (deposition date: 2022-06-08, release date: 2022-10-19, Last modification date: 2024-01-31)
Primary citation	Langley, C.,Tatsis, E.,Hong, B.,Nakamura, Y.,Paetz, C.,Stevenson, C.E.M.,Basquin, J.,Lawson, D.M.,Caputi, L.,O'Connor, S.E. Expansion of the Catalytic Repertoire of Alcohol Dehydrogenases in Plant Metabolism. Angew.Chem.Int.Ed.Engl., 61:e202210934-e202210934, 2022 Cited by PubMed: 36198083 DOI: 10.1002/anie.202210934 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (2 Å)

Structure validation