8A23

Crystal structure of SARS-CoV-2 nsp10/nsp16 methyltransferase in complex with TO383

8A23 の概要

• エントリーDOI: 10.2210/pdb8a23/pdb
• 分子名称: 2'-O-methyltransferase nsp16, Non-structural protein 10, (2R,3R,4S,5R)-2-[4-azanyl-5-(2-quinolin-3-ylethynyl)pyrrolo[2,3-d]pyrimidin-7-yl]-5-(hydroxymethyl)oxolane-3,4-diol, ... (5 entities in total)
• 機能のキーワード: viral, methyltransferase, inhibitor, viral protein
• 由来する生物種: Severe acute respiratory syndrome coronavirus 2; 詳細
• タンパク質・核酸の鎖数: 2
• 化学式量合計: 47252.85

構造登録者

Hanigovsky, M.,Krafcikova, P.,Klima, M.,Boura, E. (登録日: 2022-06-02, 公開日: 2023-06-14, 最終更新日: 2024-02-07)

• 主引用文献: Hanigovsky, M.,Krafcikova, P.,Klima, M.,Boura, E.; Crystal structure of SARS-CoV-2 nsp10/nsp16 methyltransferase in complex with TO383; To Be Published,

実験手法

X-RAY DIFFRACTION (2.8 Å)