8A17

Human PTPRM domains FN3-4, in spacegroup P3221

8A17 の概要

• エントリーDOI: 10.2210/pdb8a17/pdb
• 分子名称: Receptor-type tyrosine-protein phosphatase mu, beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-[alpha-L-fucopyranose-(1-6)]2-acetamido-2-deoxy-beta-D-glucopyranose, alpha-D-mannopyranose-(1-6)-beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-[alpha-L-fucopyranose-(1-6)]2-acetamido-2-deoxy-beta-D-glucopyranose, ... (5 entities in total)
• 機能のキーワード: receptor phosphatase, homophilic dimer, cell adhesion
• 由来する生物種: Homo sapiens (human)
• タンパク質・核酸の鎖数: 4
• 化学式量合計: 120244.30

構造登録者

Shamin, M.,Graham, S.C.,Sharpe, H.J.,Deane, J.E. (登録日: 2022-05-31, 公開日: 2023-03-15, 最終更新日: 2024-02-07)

• 主引用文献: Hay, I.M.,Shamin, M.,Caroe, E.R.,Mohammed, A.S.A.,Svergun, D.I.,Jeffries, C.M.,Graham, S.C.,Sharpe, H.J.,Deane, J.E.; Determinants of receptor tyrosine phosphatase homophilic adhesion: Structural comparison of PTPRK and PTPRM extracellular domains.; J.Biol.Chem., 299:102750-102750, 2023; PubMed: 36436563; DOI: 10.1016/j.jbc.2022.102750

実験手法

X-RAY DIFFRACTION (3.09 Å)