8ZQQ

Human high-affinity choline transporter CHT1 bound to choline under NaCl condition, with sodium and chloride ions coordinated.

Summary for 8ZQQ

• Entry DOI: 10.2210/pdb8zqq/pdb
• EMDB information: 60388
• Descriptor: High affinity choline transporter 1, beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, CHOLINE ION, ... (5 entities in total)
• Functional Keywords: transporter, structural protein
• Biological source: Homo sapiens (human)
• Total number of polymer chains: 1
• Total formula weight: 63988.30

Authors

Qiu, Y.,Gao, Y.,Zhao, Y. (deposition date: 2024-06-03, release date: 2024-12-04)

• Primary citation: Qiu, Y.,Gao, Y.; Ion coupling and inhibitory mechanisms of the human presynaptic high-affinity choline transporter CHT1; Structure, 2024; DOI: 10.1016/j.str.2024.11.009

Experimental method

ELECTRON MICROSCOPY (2.5 Å)